Low sequencing efforts bias analyses of shared taxa in microbial communities

@article{Lemos2012LowSE,
  title={Low sequencing efforts bias analyses of shared taxa in microbial communities},
  author={Leandro Nascimento Lemos and Roberta R. Fulthorpe and Luiz Fernando W{\"u}rdig Roesch},
  journal={Folia Microbiologica},
  year={2012},
  volume={57},
  pages={409-413}
}
The potential for comparing microbial community population structures has been greatly enhanced by developments in next generation sequencing methods that can generate hundreds of thousands to millions of reads in a single run. Conversely, many microbial community comparisons have been published with no more than 1,000 sequences per sample. These studies have presented data on levels of shared operational taxonomic units (OTUs) between communities. Due to lack of coverage, that approach might… CONTINUE READING
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