Low risk of impaired testicular Sertoli and Leydig cell functions in boys with isolated hypospadias.

@article{Rey2005LowRO,
  title={Low risk of impaired testicular Sertoli and Leydig cell functions in boys with isolated hypospadias.},
  author={Rodolfo Alberto Rey and Ethel Codner and Germ{\'a}n {\'I}{\~n}iguez and Patricia Bedecarr{\'a}s and Romina V Trigo and Cecilia Okuma and Silvia Gottlieb and Ignacio Bergad{\'a} and Stella M. Campo and Fernando G Cassorla},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2005},
  volume={90 11},
  pages={6035-40}
}
CONTEXT Isolated hypospadias may result from impaired testicular function or androgen end-organ defects or, alternatively, from hormone-independent abnormalities of morphogenetic events responsible for urethral seam. OBJECTIVE The objective was to evaluate the relative prevalence of hormone-dependent etiologies in boys with isolated hypospadias. DESIGN, PATIENTS, AND MAIN OUTCOME MEASURES We studied endocrine testicular capacity in 61 patients with isolated hypospadias and 28 with… CONTINUE READING
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