Low rates of expression profile divergence in highly expressed genes and tissue-specific genes during mammalian evolution.

@article{Liao2006LowRO,
  title={Low rates of expression profile divergence in highly expressed genes and tissue-specific genes during mammalian evolution.},
  author={Ben-Yang Liao and Jianzhi Zhang},
  journal={Molecular biology and evolution},
  year={2006},
  volume={23 6},
  pages={1119-28}
}
Evolutionary rates provide important information about the pattern and mechanism of evolution. Although the rate of gene sequence evolution has been well studied, the rate of gene expression evolution is poorly understood. In particular, it is unclear whether the gene expression level and tissue specificity influence the divergence of expression profiles between orthologous genes. Here we address this question using a microarray data set comprising the expression signals of 10,607 pairs of… CONTINUE READING