Low rate of ret proto-oncogene activation (PTC/retTPC) in papillary thyroid carcinomas from Saudi Arabia.

@article{Zou1994LowRO,
  title={Low rate of ret proto-oncogene activation (PTC/retTPC) in papillary thyroid carcinomas from Saudi Arabia.},
  author={Minjing Zou and Yan Fen Shi and Nadir Rashad Farid},
  journal={Cancer},
  year={1994},
  volume={73 1},
  pages={176-80}
}
BACKGROUND The ret proto-oncogene activation (PTC/retTPC oncogene) in thyroid papillary carcinoma has been reported in different populations with different frequencies. Thyroid papillary carcinoma appears to behave more aggressively in the Persian Gulf region than elsewhere. In the current study, the frequency of PTC/retTPC oncogene in thyroid tumors from Saudi Arabia was investigated. METHODS PTC/retTPC oncogene transcripts were analyzed by the polymerase chain reaction amplification of cDNA… CONTINUE READING