Low-protein diet impairs vascular relaxation in virgin and pregnant rats.

@article{Koumentaki2002LowproteinDI,
  title={Low-protein diet impairs vascular relaxation in virgin and pregnant rats.},
  author={Angeliki Koumentaki and Frederick Anthony and Lucilla Poston and Timothy Wheeler},
  journal={Clinical science},
  year={2002},
  volume={102 5},
  pages={553-60}
}
Pregnancy is associated with increases in maternal cardiac output and plasma volume and a reduction in peripheral vascular resistance. Cardiac output and plasma volume are substantially reduced in pregnant rats fed a low-protein diet, but it is not known whether vascular function is also compromised. We have investigated vascular function in virgin and pregnant Wistar rats subjected to dietary protein restriction [9% (w/v) casein, compared with 18% (w/v) casein for controls]. The diets were fed… CONTINUE READING

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