Low prostate-specific antigen and no Gleason score upgrade despite more extensive cancer during active surveillance predicts insignificant prostate cancer at radical prostatectomy.

@article{Han2012LowPA,
  title={Low prostate-specific antigen and no Gleason score upgrade despite more extensive cancer during active surveillance predicts insignificant prostate cancer at radical prostatectomy.},
  author={Jeong Seok Han and Adam D. Toll and Ali Reja Mohammad Ruhul Amin and Herbert Ballentine Carter and Patricia B Landis and Stephen Q. S. Lee and Jonathan I. Epstein},
  journal={Urology},
  year={2012},
  volume={80 4},
  pages={883-8}
}
OBJECTIVE To identify parameters that predict insignificant prostate cancer in 67 radical prostatectomies after biopsy reclassification to worse disease on active surveillance. METHODS Parameters evaluated at diagnosis and at biopsy reclassification included serum prostate-specific antigen, prostate-specific antigen density, number of positive cores, maximum percent involvement of cancer per core, and any interval negative biopsies. Gleason upgrading at biopsy reclassification was also… CONTINUE READING
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