Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus

@inproceedings{Bengtsson2014LowPO,
  title={Low production of reactive oxygen species in granulocytes is associated with organ damage in systemic lupus erythematosus},
  author={Anders A. Bengtsson and {\AA}sa Pettersson and Stina Wichert and B Gullstrand and Markus Hansson and Thomas Hellmark and Asa C M Johansson},
  booktitle={Arthritis research & therapy},
  year={2014}
}
INTRODUCTION Polymorphonuclear leukocytes (PMN) are main effector cells in the acute immune response. While the specific role of PMN in systemic lupus erythematosus (SLE) and autoimmunity is still unclear, their importance in chronic inflammation is gaining more attention. Here we investigate aspects of function, bone marrow release and activation of PMN in patients with SLE. METHODS The following PMN functions and subsets were evaluated using flow cytometry; (a) production of reactive oxygen… CONTINUE READING
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erythematosus

  • E Eksioglu-Demiralp, H Direskeneli, A Kibaroglu, S Yavuz, T Ergun, T Akoglu
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