[Low prevalence of hepatitis B virus primary drug resistance in Southern Spain].

Abstract

INTRODUCTION To know the prevalence of primary resistance in chronic hepatitis B naïve patients is essential to decide on the need of routine laboratory testing. PATIENTS AND METHODS The genetic sequence of the HBV polymerase from 105naïve patients was analysed. RESULTS rtV173L, a lamivudine compensatory mutation, was detected in two patients (1.9%), rtI233V in one patient, and another one carried the sG145R vaccine escape mutation. CONCLUSION Our study shows that studying HBV resistance in naïve patients should not be recommended in the routine laboratory setting, for the time being.

DOI: 10.1016/j.eimc.2013.02.014

Cite this paper

@article{Estvez2013LowPO, title={[Low prevalence of hepatitis B virus primary drug resistance in Southern Spain].}, author={Marta {\'A}lvarez Est{\'e}vez and Natalia Chueca-Porcuna and Vicente Guillot-Suay and Alejandro Pe{\~n}a-Monje and Fernando Garc{\'i}a-Garc{\'i}a and Federico Garc{\'i}a-Garc{\'i}a}, journal={Enfermedades infecciosas y microbiología clínica}, year={2013}, volume={31 8}, pages={520-2} }