Low oxygen concentrations for embryo culture in assisted reproductive technologies.

@article{Bontekoe2012LowOC,
  title={Low oxygen concentrations for embryo culture in assisted reproductive technologies.},
  author={Stephan Bontekoe and Eleni Mantikou and Madelon van Wely and Srividya Seshadri and Sjoerd Repping and S Mastenbroek},
  journal={The Cochrane database of systematic reviews},
  year={2012},
  volume={7},
  pages={CD008950}
}
BACKGROUND During in vitro fertilisation (IVF) procedures, human preimplantation embryos are cultured in the laboratory. While some laboratories culture in an atmospheric oxygen concentration (˜ 20%), others use a lower concentration (˜ 5%) as this is more comparable to the oxygen concentration observed in the oviduct and the uterus. Animal studies have shown that high oxygen concentration could have a negative impact on embryo quality via reactive oxygen species causing oxidative stress. In… CONTINUE READING

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