Low-output syndrome after heart surgery: is a monotherapy with phosphodiesterase-III inhibitors feasible? A comparative study of amrinone and enoximone.

@article{Zerkowski1992LowoutputSA,
  title={Low-output syndrome after heart surgery: is a monotherapy with phosphodiesterase-III inhibitors feasible? A comparative study of amrinone and enoximone.},
  author={H. R. Zerkowski and M. G{\"u}nnicker and Uri Freund and Hans Armin Dieterich and Hans-Joachim Dre\ssler and Norbert W. Doetsch and Maria Schieffer and K Hakim-Meibodi and Jean D. Lockhart and J{\"u}rgen Christoph Reidemeister},
  journal={The Thoracic and cardiovascular surgeon},
  year={1992},
  volume={40 6},
  pages={371-7}
}
In order to determine whether the primary use of a phosphodiesterase-III (PDE) inhibitor as monotherapy for severe cardiac low-output states (LOS) is in fact practicable, we investigated the haemodynamic effects of amrinone and enoximone in a prospective randomized study. After elective CABG, AVR, or MVR, patients with cardiac LOS were given amrinone (n… CONTINUE READING