Low-normal or high-normal thyrotropin target levels during treatment of hypothyroidism: a prospective, comparative study.

@article{Boeving2011LownormalOH,
  title={Low-normal or high-normal thyrotropin target levels during treatment of hypothyroidism: a prospective, comparative study.},
  author={Anke Boeving and Gilberto Paz-Filho and Rosana Bento Radominski and Hans -F. Graf and Gisah Amaral de Carvalho},
  journal={Thyroid : official journal of the American Thyroid Association},
  year={2011},
  volume={21 4},
  pages={355-60}
}
BACKGROUND Recent literature advocates the decrease of the upper limit of the normal thyrotropin (TSH) reference range. The objective of this study was to determine whether treated hypothyroid patients maintained within a low-normal TSH range (0.4-2.0 mIU/L) have better clinical outcomes than those maintained within a high-normal TSH range (2.0-4.0 mIU/L). METHODS The study was performed in a thyroid outpatient clinic of a tertiary hospital. This was a prospective, interventional study. Forty… CONTINUE READING
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