Low-molecular-weight heparins: an intriguing new twist with profound implications.

@article{Antman1998LowmolecularweightHA,
  title={Low-molecular-weight heparins: an intriguing new twist with profound implications.},
  author={Elliott M. Antman and Robert I. Handin},
  journal={Circulation},
  year={1998},
  volume={98 4},
  pages={
          287-9
        }
}
Modern antithrombotic therapy for acute coronary syndromes rests on a growing body of basic and clinical evidence that rupture or erosion of the surface of a vulnerable plaque sets in motion a sequence of events culminating in thrombus formation in the culprit vessel. 1 When the contents of a vulnerable plaque are exposed to the bloodstream, platelets adhere to the subendothelial matrix, release ADP and thromboxane A2, and amplify the generation of thrombin. 2 As a result, a platelet aggregate… CONTINUE READING

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