Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD women.

@article{Mello2005LowmolecularweightHL,
  title={Low-molecular-weight heparin lowers the recurrence rate of preeclampsia and restores the physiological vascular changes in angiotensin-converting enzyme DD women.},
  author={Giorgio Mello and Elena Parretti and Cinzia Fatini and Chiara Riviello and Francesca Gensini and Mauro Marchionni and Gian Franco Scarselli and Gian Franco Gensini and Rosanna Abbate},
  journal={Hypertension},
  year={2005},
  volume={45 1},
  pages={86-91}
}
Data from literature report that angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism affects the recurrence of preeclampsia and that low-molecular-weight heparin (LMWH) prevents adverse outcomes in thrombophilic women. We investigated the effect of LMWH on the pregnancy outcome, on maternal blood pressure values, and on uteroplacental flow in ACE DD nonthrombophilic women with history of preeclampsia. Eighty nonthrombophilic ACE DD women were randomized in 2 groups: 41… CONTINUE READING

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