Low-molecular-mass antioxidants in parasites.

  title={Low-molecular-mass antioxidants in parasites.},
  author={R Luise Krauth-Siegel and Alejandro E. Leroux},
  journal={Antioxidants & redox signaling},
  volume={17 4},
SIGNIFICANCE Parasitic infections continue to be a major problem for global human health. Vaccines are practically not available and chemotherapy is highly unsatisfactory. One approach toward a novel antiparasitic drug development is to unravel pathways that may be suited as future targets. Parasitic organisms show a remarkable diversity with respect to the nature and functions of their main low-molecular-mass antioxidants and many of them developed pathways that do not have a counterpart in… CONTINUE READING