Low-magnitude whole-body vibration does not enhance the anabolic skeletal effects of intermittent PTH in adult mice.

@article{Lynch2011LowmagnitudeWV,
  title={Low-magnitude whole-body vibration does not enhance the anabolic skeletal effects of intermittent PTH in adult mice.},
  author={Michelle A. Lynch and Michael D. Brodt and Abby L. Stephens and Roberto Civitelli and M. J. Vaz-da Silva},
  journal={Journal of orthopaedic research : official publication of the Orthopaedic Research Society},
  year={2011},
  volume={29 4},
  pages={465-72}
}
Whole-body vibration (WBV) is a low-magnitude mechanical stimulus that may be anabolic for bone, yet we recently found that WBV did not improve bone properties in adult mice. Because intermittent parathyroid hormone (PTH) enhances the anabolic effects of high-magnitude skeletal loading, we sought to determine the skeletal effects of WBV in combination with PTH. Seven-month-old male BALB/c mice were assigned to six groups (n = 13-14/group) based on magnitude of applied acceleration (0 or 0.3 G… CONTINUE READING

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