Low mRNA expression of the apoptosis-related genes CASP3, CASP8, and FAS is associated with low induction treatment response in childhood acute lymphoblastic leukemia (ALL).

@article{Mata2010LowME,
  title={Low mRNA expression of the apoptosis-related genes CASP3, CASP8, and FAS is associated with low induction treatment response in childhood acute lymphoblastic leukemia (ALL).},
  author={Juliana F. Mata and Vanessa da Silva Silveira and Elvis Cristian Cueva Mateo and Maria Angelica Cortez and Rosane de Paula Queiroz and Jos{\'e} Andres Yunes and Maria Lucia Martino Lee and Silvia Regina Caminada Toledo and Antonio S{\'e}rgio Petrilli and S{\'i}lvia Regina Brandalise and Luiz Gonzaga Tone and Carlos Alberto Scrideli},
  journal={Pediatric blood & cancer},
  year={2010},
  volume={55 1},
  pages={
          100-7
        }
}
BACKGROUND Defects in apoptosis signaling have been considered to be responsible for treatment failure in many types of cancer, although with controversial results. The objective of the present study was to assess the expression profile of key apoptosis-related genes in terms of clinical and biological variables and of the survival of children with acute lymphoblastic leukemia (ALL). PROCEDURE The levels of mRNA expression of the apoptosis-related genes CASP3, CASP8, CASP9, FAS, and BCL2 were… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 11 CITATIONS

References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Similar Papers

Loading similar papers…