Low levels of IGFBP7 expression in high-grade serous ovarian carcinoma is associated with patient outcome

@inproceedings{Gambaro2015LowLO,
  title={Low levels of IGFBP7 expression in high-grade serous ovarian carcinoma is associated with patient outcome},
  author={Karen Gambaro and Michael C. J. Quinn and Katia Y. C{\'a}ceres-Gorriti and Rebecca S Shapiro and Diane Mich{\`e}le Provencher and Kurosh Rahimi and Anne-Marie Mes-Masson and Patricia N. Tonin},
  booktitle={BMC Cancer},
  year={2015}
}
Insulin-like growth factor binding protein 7 (IGFBP7) has been suggested to act as a tumour suppressor gene in various human cancers, yet its role in epithelial ovarian cancer (EOC) has not yet been investigated. We previously observed that IGFBP7 was one of several genes found significantly upregulated in an EOC cell line model rendered non-tumourigenic as consequence of genetic manipulation. The aim of the present study was to investigate the role of IGFBP7 in high-grade serous ovarian… CONTINUE READING
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