Low-intensity ultrasound increased colony forming unit-fibroblasts of mesenchymal stem cells during primary culture.

@article{Choi2011LowintensityUI,
  title={Low-intensity ultrasound increased colony forming unit-fibroblasts of mesenchymal stem cells during primary culture.},
  author={Woo Hee Choi and Byung Hyune Choi and Byoung-hyun Min and So Ra Park},
  journal={Tissue engineering. Part C, Methods},
  year={2011},
  volume={17 5},
  pages={517-26}
}
Mesenchymal stem cells (MSCs) from bone marrow (BM) are an attractive cell source for stem cell-based therapeutic applications, but they exist at low-end ratios, which further decreases along with increased donor age. Thus, for clinical applications, there is a high demand for large numbers of active MSCs. This study investigated if low-intensity ultrasound (LIUS), a special type of mechanical stimulation, could increase the yield of MSCs during primary culture from the BM. Cultures were… CONTINUE READING

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