Low incidence of cardiac events with beta-blocking therapy in children with long QT syndrome.

@article{Villain2004LowIO,
  title={Low incidence of cardiac events with beta-blocking therapy in children with long QT syndrome.},
  author={Elisabeth Villain and Isabelle Denjoy and Jean Marc Lupoglazoff and Pascale Guicheney and Bernard Hainque and Vincent Lucet and Damien Bonnet},
  journal={European heart journal},
  year={2004},
  volume={25 16},
  pages={1405-11}
}
AIMS To evaluate the effect of beta-blockers in children with long QT syndrome (LQTS) we reviewed the outcome of 122 patients (pts). METHODS LQTS was diagnosed in 24 neonates and in 98 pts aged 0.5-15 years. Diagnosis was made because of syncope in 51 pts, bradycardia in 10 neonates and family history in 61 pts. The longest QTc ranged from 400 to 700 ms. Thirteen pts had 2:1 atrioventricular block and/or ventricular arrhythmias. Screening for mutations was performed in 118 pts. All children… CONTINUE READING