Low-grade systemic inflammation, hypoadiponectinemia and a high concentration of leptin are present in very young obese children, and correlate with metabolic syndrome.

@article{Valle2005LowgradeSI,
  title={Low-grade systemic inflammation, hypoadiponectinemia and a high concentration of leptin are present in very young obese children, and correlate with metabolic syndrome.},
  author={Miguel G. Vel{\'a}zquez-del Valle and Rub{\'e}n Fern{\'a}ndez Martos and F{\'e}lix Gasc{\'o}n and Rafael Fernandez de Ca{\~n}ete and Mario Adrian M. Zafra and Rosa Amalia Morales},
  journal={Diabetes & metabolism},
  year={2005},
  volume={31 1},
  pages={
          55-62
        }
}
OBJECTIVE To determine the concentration levels of C-reactive protein (CRP), leptin and adiponectin in obese pre-pubertal children, and their possible relation with metabolic syndrome, fibrinogen and plasminogen activator inhibitor-1. METHODS A study was carried out in 51 obese children (aged 6 to 9 years) and the same number of non-obese children (control group), matched by age and sex. (Cross-sectional study of obese children). Body mass index (BMI), waist/hip ratio (WHR) and blood pressure… CONTINUE READING
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