Low-grade malignant perineurioma of the paravertebral column, transforming into a high-grade malignancy.

@article{Karaki1999LowgradeMP,
  title={Low-grade malignant perineurioma of the paravertebral column, transforming into a high-grade malignancy.},
  author={S Karaki and Joji Mochida and Yong Ho Lee and Koichi Nishimura and Yutaka Tsutsumi},
  journal={Pathology international},
  year={1999},
  volume={49 9},
  pages={820-5}
}
A demarcated 6 x 5 cm right paravertebral tumor at the level of T6 in a 39-year-old male was removed surgically. Histologically, the tumor consisted of monomorphous benign-looking, low-cellular spindle cells embedded in desmoplastic stroma. Ten years later, the tumor recurred locally with metastasis to systemic organs, including the occipital skin. Malignancy was histologically evident by the increased cellularity, cellular atypia and mitotic activity. The patient died of respiratory failure at… CONTINUE READING