Low-grade inflammation plays a pivotal role in gastrointestinal dysfunction in irritable bowel syndrome.

Abstract

The pathogenesis of irritable bowel syndrome (IBS) is considered to be multifactorial and includes psychosocial factors, visceral hypersensitivity, infection, microbiota and immune activation. It is becoming increasingly clear that low-grade inflammation is present in IBS patients and a number of biomarkers have emerged. This review describes the evidence… (More)
DOI: 10.4291/wjgp.v1.i3.97

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