Low-grade endotoxemia in patients with severe autism.

@article{Emanuele2010LowgradeEI,
  title={Low-grade endotoxemia in patients with severe autism.},
  author={Enzo Emanuele and Paolo Orsi and Marianna Boso and Davide Broglia and Natascia Brondino and Francesco Barale and Stefania Ucelli di Nemi and Pierluigi Politi},
  journal={Neuroscience letters},
  year={2010},
  volume={471 3},
  pages={162-5}
}
The objective of this study was to examine whether levels of endotoxin and other markers of immuno-inflammatory activation are altered in adult patients with severe autism. We determined circulating serum endotoxin levels, its soluble receptor (sCD14), and markers of immuno-inflammatory activation (IL-1beta, IL-6, and IL-10) in 22 adult patients with severe autism and 28 age- and gender-matched healthy controls. Compared with healthy subjects, serum levels of endotoxin were significantly higher… CONTINUE READING
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