Low-frequency ultrasound penetrates the cranium and enhances thrombolysis in vitro.

@article{Akiyama1998LowfrequencyUP,
  title={Low-frequency ultrasound penetrates the cranium and enhances thrombolysis in vitro.},
  author={Masashi Akiyama and Toshihiro Ishibashi and Takatsugu Yamada and Hiroshi Furuhata},
  journal={Neurosurgery},
  year={1998},
  volume={43 4},
  pages={
          828-32; discussion 832-3
        }
}
OBJECTIVE Refinements of treatment methods are sought to rapidly reduce the volume of intracranial clots and to decrease patient exposure to possible complications of thrombolytic therapy for intracranial hematomas. We assessed the possibility of adding ultrasonication using model systems including human blood clots and temporal bone in vitro. METHODS The transmittance of ultrasound through temporal bone obtained at autopsy was compared between the frequencies 211.5 KHz and 1.03 MHz, using a… CONTINUE READING
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