Low-frequency stimulation of the perforant path produces long-term potentiation in the dentate gyrus of unanesthetized rats.

Abstract

Brief periods of high-frequency stimulation of hippocampal afferents produce long-term potentiation (LTP) of synaptic transmission, but the minimum frequency capable of inducing this alteration in synaptic efficacy has not been specified. The present study used the repeated measurement of input-output curves in the perforant path - dentate gyrus system of… (More)

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