Low frequency rTMS of the SMA transiently ameliorates peak-dose LID in Parkinson’s disease

@article{Brusa2006LowFR,
  title={Low frequency rTMS of the SMA transiently ameliorates peak-dose LID in Parkinson’s disease},
  author={Livia Brusa and Viviana Versace and Giacomo Koch and Cesare Iani and Diego Centonze},
  journal={Clinical Neurophysiology},
  year={2006},
  volume={117},
  pages={1917-1921}
}
OBJECTIVE To determine whether low-frequency repetitive transcranial magnetic stimulation (rTMS) may modulate l-DOPA-induced dyskinesia (LID) in dyskinetic Parkinson's disease (PD) patients. LID is a severe motor complication in advanced PD patients. The neural mechanisms involved in LID are not clear, and it is apparent that both an excessive decrease in internal pallidus firing and a modification and overactivation of cortical motor and premotor areas are involved in its pathogenesis… CONTINUE READING

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