Low folate status enhances pregnancy changes in plasma betaine and dimethylglycine concentrations and the association between betaine and homocysteine.

Abstract

BACKGROUND Folate, choline, and betaine participate in homocysteine metabolism. It is not known whether they interact during pregnancy. OBJECTIVE The objective was to investigate how folate status affects choline, betaine, and dimethylglycine during pregnancy. DESIGN Fasting plasma folate, cobalamin, free choline, betaine, dimethylglycine, and total… (More)
DOI: 10.3945/ajcn.112.054189

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