Low expression level of Dickkopf 4 in hepatocellular carcinoma and its clinical significance

@inproceedings{Cui2016LowEL,
  title={Low expression level of Dickkopf 4 in hepatocellular carcinoma and its clinical significance},
  author={Dan Dan Cui and Zhi Wang and Tao Wang and Xiaoyin Tang and Bo Zhai},
  year={2016}
}
Purpose: To study the clinical significance of Dickkopf 4 in hepatocellular Carcinoma. Methods: The expression of DKK4 and beta-catenin was analyzed by real-time qPCR and immunohistochemistry. Patient’s prognosis was evaluated through clinical follow-up. Results: DKK4 was expressed at a low level in HCC tissues, while betacatenin was highly expressed (P < 0.05). The expression of beta-catenin and that of DKK4 at the protein level was negatively correlated, with r = -0.4, P = 0.006. The… CONTINUE READING
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