Low ethanol concentrations enhance GABAergic inhibitory postsynaptic potentials in hippocampal pyramidal neurons only after block of GABAB receptors.

@article{Wan1996LowEC,
  title={Low ethanol concentrations enhance GABAergic inhibitory postsynaptic potentials in hippocampal pyramidal neurons only after block of GABAB receptors.},
  author={F. J. Wan and Fr{\'e}d{\'e}rique Berton and Samuel G. Madamba and Walter Francesconi and George Robert Siggins},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 10},
  pages={5049-54}
}
Despite considerable evidence that ethanol can enhance chloride flux through the gamma-aminobutyric acid type A (GABA/A/) receptor-channel complex in several central neuron types, the effect of ethanol on hippocampal GABAergic systems is still controversial. Therefore, we have reevaluated this interaction in hippocampal pyramidal neurons subjected to local monosynaptic activation combined with pharmacological isolation of the various components of excitatory and inhibitory synaptic potentials… CONTINUE READING

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