Low doses of ethanol reduce neurotensin levels in discrete brain regions from LS/Ibg and SS/Ibg mice.

@article{Erwin1990LowDO,
  title={Low doses of ethanol reduce neurotensin levels in discrete brain regions from LS/Ibg and SS/Ibg mice.},
  author={V. Gene Erwin and Byron C Jones and Richard Radcliffe},
  journal={Alcoholism, clinical and experimental research},
  year={1990},
  volume={14 1},
  pages={42-7}
}
Studies were designed to examine the previously proposed hypothesis that some of the pharmacological actions of ethanol are mediated by neurotensinergic processes. Neurotensin-immunoreactivity (NT-ir) was extracted from various brain regions and shown by high performance liquid chromatography to possess the same retention time as authentic bovine NT1-13. The highest levels of NT-ir were observed in the hypothalamus with intermediate levels in the midbrain and striatum and lowest levels in the… CONTINUE READING