Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis.

@article{Lanas2011LowDO,
  title={Low doses of acetylsalicylic acid increase risk of gastrointestinal bleeding in a meta-analysis.},
  author={A. Iriarte Lanas and Ping Wu and Jennie Medin and Edward Mills},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2011},
  volume={9 9},
  pages={762-768.e6}
}
BACKGROUND & AIMS We performed a meta-analysis of data from randomized trials to estimate the risk of all-cause mortality and bleeding (and especially gastrointestinal [GI] bleeding) in patients treated with low doses of acetylsalicylic acid (ASA) (75-325 mg/d), alone or in combination with other medications. METHODS We searched 10 electronic databases (until October 2010) and collected data on adverse events in randomized controlled studies that evaluated low doses of ASA, alone (35 trials… CONTINUE READING
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