Low-dose thoracoabdominal irradiation for the treatment of refractory chronic graft-versus-host disease.

Abstract

BACKGROUND Half of the patients with chronic graft-versus-host disease (GvHD) do not achieve a complete remission with first-line therapy. No clear recommendations are available regarding second-line treatments. METHODS We retrospectively report our single-center experience of low-dose thoracoabdominal irradiation (1-Gy TAI) in 41 patients with refractory… (More)

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