[Low-dose spiral CT of the lung in the follow-up of non-malignant lung disease].


PURPOSE To assess image quality of chest CT with an 80 to 90 percent dose reduction in follow-up studies of patients with lung disease, dose and image quality of a low-dose protocol was investigated. MATERIALS AND METHODS A follow-up low-dose CT (ND-CT, 120 kV, 10 mAs/slice, 3 mm slice thickness) was performed on 35 patients with non-malignant lung disease and compared with the initial standard dose CT (= SD-CT, 100 mAs/slice, 3 or 5 mm slice thickness). The dose was measured by thermo-luminescence in an Alderson phantom. Image quality was assessed by four independent radiologists in six perihilar, central and peripheral lung regions using a 4-point-scale ("very good", "good", "moderate", and "poor"). RESULTS Effective dose was 0.5 mSv for ND-CT and 4.0 - 5.0 mSv for SD-CT. The ratings "very good"/"good" were given in the perihilar regions in ND-CT 97.5 % versus SD-CT 99.3 % (n. s.), in the central regions in ND-CT 96.4 % versus SD-CT 94.6 % (n. s.), and in the peripheral regions in ND-CT 70.0 % versus SD-CT 88.2 % (p < 0.01). CONCLUSION Follow-up CT of pulmonary structures in patients with chronic lung disease can be performed with substantial dose reduction. A decrease of image quality may result in peripheral lung regions.


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@article{Coppenrath2004LowdoseSC, title={[Low-dose spiral CT of the lung in the follow-up of non-malignant lung disease].}, author={Eva M. Coppenrath and Ullrich Mueller-Lisse and Ursula Lechel and Ronja Veit and Ch. Weber and Sandra Banac and R. Eibel and Harro Bitterling and Claudia De Lorenzo and Rainald Fischer and Tobias Meindl and M. Reiser}, journal={RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin}, year={2004}, volume={176 4}, pages={522-8} }