Low dose mixture effects of endocrine disrupters and their implications for regulatory thresholds in chemical risk assessment.

@article{Kortenkamp2014LowDM,
  title={Low dose mixture effects of endocrine disrupters and their implications for regulatory thresholds in chemical risk assessment.},
  author={Andreas Kortenkamp},
  journal={Current opinion in pharmacology},
  year={2014},
  volume={19},
  pages={105-11}
}
Today's chemical exposures are characterised by a widely spread blanket of contamination composed of myriads of chemicals, many of them endocrine disrupters, all at rather low levels. With their focus on considering single chemicals one by one, the approaches used by regulatory bodies worldwide for safety assessments of chemicals cannot keep up with these pollution patterns. A substantial challenge lies in the assessment of combination effects from large numbers of endocrine disrupters and… CONTINUE READING

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