Low-dose mistletoe lectin-I reduces melanoma growth and spread in a scid mouse xenograft model

Abstract

This study investigates the effects of mistletoe lectin-I (ML-I) on melanoma growth and spread in vivo. The human melanoma cell line MV3 was xenografted into severe combined immunodeficient mice and vehicle solution or purified ML-I was administered at 30, 150 and 500 ng per kg body weight (20 mice per group) daily. After 19 days, mice were killed, primary… (More)
DOI: 10.1038/sj.bjc.6604106

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