Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting

@article{Pae2006LowdoseMM,
  title={Low-dose mirtazapine may be successful treatment option for severe nausea and vomiting},
  author={Chi-Un Pae},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2006},
  volume={30},
  pages={1143-1145}
}
  • C. Pae
  • Published 30 August 2006
  • Psychology, Medicine
  • Progress in Neuro-Psychopharmacology and Biological Psychiatry
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Central Neuromodulators for Treating Functional GI Disorders: A Primer
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Patients with functional GI disorders (FGIDs) are commonplace in the gastroenterologist's practice and there are benefits and potential adverse effects to using TCAs, SSRs, SNRIs, atypical antipsychotics, and miscellaneous central neuromodulators in these patients.
Newest Drugs for Chronic Unexplained Nausea and Vomiting
  • W. Hasler
  • Medicine
    Current Treatment Options in Gastroenterology
  • 2016
TLDR
Current investigations will define potential therapeutic actions of agents that stimulate gastric emptying via action on gastroduodenal serotonin, motilin, and ghrelin receptors, which may broaden the treatment options for refractory cases of unexplained nausea and vomiting.
An Open-Label Long-Term Naturalistic Study of Mirtazapine Treatment for Depression in Cancer Patients
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Relatively low doses of mirtazapine appeared to be safe and effective for treating cancer patients undergoing radiotherapy and/or chemotherapy, and the reduction in the severity of depressive symptoms was maintained until the end of the 24-week treatment period.
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A case of SSRI-induced nausea successfully treated with mirtazapine is reported, and the 5-HT antagonist cyproheptadine is associated with worsening of depressive symptoms when used to treat SSri-induced sexual dysfunction.
Mirtazapine (Remeron™) as Treatment for Non-Mechanical Vomiting after Gastric Bypass
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It is concluded that mirtazapine may be a successful option to treat non-mechanical postoperative vomiting in morbidly obese patients after gastric bypass.
Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy
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Nausea and vomiting disappeared within hours, pregnancy termination was no longer desired and the patient was discharged two weeks later in good health and at 36 weeks gestation a cesarean section was performed.
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This report describes that addition of the new antidepressant mirtazapine may ameliorate nausea induced by serotonin reuptake-inhibiting antidepressants, presumably via 5-HT 3 receptor blockade.
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