Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial
@article{Hertzen2002LowDM, title={Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial}, author={H. Hertzen and G. Piaggio and A. Peregoudov and J. Ding and F. T. W. R. G. O. P. M. O. Regulation}, journal={The Lancet}, year={2002}, volume={360}, pages={1803-1810} }
BACKGROUND
A single 10 mg dose of mifepristone, and two 0.75 mg doses of levonorgestrel 12 h apart, are effective for emergency contraception. Because no studies had compared the efficacies of both compounds, or investigated a single dose of 1.5 mg levonorgestrel, we undertook this three-arm trial.
METHODS
We did a randomised, double-blind trial in 15 family-planning clinics in 10 countries. We randomly assigned 4136 healthy women with regular menstrual cycles, who requested emergency… CONTINUE READING
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References
SHOWING 1-10 OF 15 REFERENCES
Comparison of three single doses of mifepristone as emergency contraception: a randomised trial
- Medicine
- The Lancet
- 1999
- 58
- PDF
Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception
- Medicine
- 1998
- 460
[A randomized, double-blind, multicentre study on comparing levonorgestrel and mifepristone for emergency contraception].
- Medicine
- Zhonghua fu chan ke za zhi
- 1999
- 24
A prospective randomized comparison of levonorgestrel with the Yuzpe regimen in post-coital contraception.
- Medicine
- Human reproduction
- 1993
- 251
New estimates of the effectiveness of the Yuzpe regimen of emergency contraception.
- Medicine
- Contraception
- 1998
- 298