Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events.

@article{Saag1994LowDL,
  title={Low dose long-term corticosteroid therapy in rheumatoid arthritis: an analysis of serious adverse events.},
  author={Kenneth G. Saag and Rachelle Koehnke and John Richard Caldwell and Richard D. Brasington and Leon F. Burmeister and Bridget Zimmerman and Janice A Kohler and Daniel E. Furst},
  journal={The American journal of medicine},
  year={1994},
  volume={96 2},
  pages={
          115-23
        }
}
PURPOSE The purpose of this study was to better define the toxicity of low dose (less than or equal to 15 mg/d prednisone or equivalent) long-term (greater than 1 year) corticosteroids in the treatment of rheumatoid arthritis (RA). PATIENTS AND METHODS We examined an historical cohort of 112 RA patients on low dose (6.1 +/- 3.1 mg/d, mean +/- SD) long-term (6.2 +/- 4.6 years) prednisone (CS) and compared them to 112 matched RA patients not using prednisone (CO). CS were matched one-to-one… CONTINUE READING
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