Low-dose intravenous midazolam reduces etomidate-induced myoclonus: a prospective, randomized study in patients undergoing elective cardioversion.

@article{Hueter2007LowdoseIM,
  title={Low-dose intravenous midazolam reduces etomidate-induced myoclonus: a prospective, randomized study in patients undergoing elective cardioversion.},
  author={Lars Hueter and Torsten Schreiber and Michael Gugel and Konrad R G Schwarzkopf},
  journal={Anesthesia and analgesia},
  year={2007},
  volume={105 5},
  pages={1298-302, table of contents}
}
BACKGROUND Myoclonic movements are a common problem in unpremedicated patients during induction of anesthesia with etomidate. METHODS In a double-blind fashion, 40 patients (ASA physical status III-IV) scheduled for elective cardioversion were randomly assigned to receive either 0.015 mg/kg midazolam or placebo 90 s before the injection of 0.3 mg/kg etomidate. Myoclonic movements and sedation were recorded on a scale between 0 and 3. Pulse oximetry, noninvasive arterial blood pressure, and… CONTINUE READING

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