Low dose intravenous immunoglobulins and steroids in toxic epidermal necrolysis: a prospective comparative open-labelled study of 36 cases.

@article{Jagadeesan2013LowDI,
  title={Low dose intravenous immunoglobulins and steroids in toxic epidermal necrolysis: a prospective comparative open-labelled study of 36 cases.},
  author={Soumya Jagadeesan and Kunjumani Sobhanakumari and Sadeep Melethil Sadanandan and Sheeba Ravindran and Manjula Velikkakathu Divakaran and Lissy Skaria and George Elias Kurien},
  journal={Indian journal of dermatology, venereology and leprology},
  year={2013},
  volume={79 4},
  pages={506-11}
}
BACKGROUND Toxic epidermal necrolysis (TEN) is a severe adverse drug reaction associated with high mortality. Though different modalities of treatment are advocated, there is no consensus regarding specific therapy. Corticosteroids have shown conflicting results and for high dose intravenous immunoglobulins (IVIG), cost is a limiting factor. AIM To find out the effectiveness of combination therapy with low-dose IVIG and steroids versus steroids alone in our TEN patients. METHODS After… CONTINUE READING
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