Low-dose hydrocortisone during severe sepsis: effects on microalbuminuria.

  title={Low-dose hydrocortisone during severe sepsis: effects on microalbuminuria.},
  author={Simone Rinaldi and Chiara Adembri and Seren{\`e}lla Grechi and Angelo Raffaele de Gaudio},
  journal={Critical care medicine},
  volume={34 9},
OBJECTIVE The aim of this study was to investigate the effect of low-dose hydrocortisone on glomerular permeability measured by the microalbuminuria to creatinine ratio (MACR) and on other markers of sepsis in severe septic patients. DESIGN Randomized prospective study. SETTING University intensive care unit. PATIENTS The study involved 40 patients with severe sepsis randomized into the hydrocortisone group (n = 20) and the standard therapy group (n = 20). INTERVENTIONS The… CONTINUE READING

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