Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen.

Abstract

Despite decades of research in defining the health effects of low-dose (<100 mGy) ionizing photon radiation (LDR), the relationship between LDR and human cancer risk remains elusive. Because chemical carcinogens modify the tumor microenvironment, which is critical for cancer development, we investigated the role and mechanism of LDR in modulating the… (More)
DOI: 10.1093/carcin/bgs159

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@article{Chen2012LowdoseGI, title={Low-dose gamma-irradiation inhibits IL-6 secretion from human lung fibroblasts that promotes bronchial epithelial cell transformation by cigarette-smoke carcinogen.}, author={Wenshu Chen and Xiuling Xu and Lang Bai and Mabel T. Padilla and Katherine M Gott and Shuguang Leng and Carmen Tellez and Julie A. Wilder and Steven Alan Belinsky and Bobby R. Scott and Yong Lin}, journal={Carcinogenesis}, year={2012}, volume={33 7}, pages={1368-74} }