Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos.

@article{Duan2016LowdoseEO,
  title={Low-dose exposure of silica nanoparticles induces cardiac dysfunction via neutrophil-mediated inflammation and cardiac contraction in zebrafish embryos.},
  author={Junchao Duan and Yang Yu and Yang Li and Yanbo Li and Hongcui Liu and Li Jing and Man Yang and Ji Wang and Chunqi Li and Zhiwei Sun},
  journal={Nanotoxicology},
  year={2016},
  volume={10 5},
  pages={575-85}
}
The toxicity mechanism of nanoparticles on vertebrate cardiovascular system is still unclear, especially on the low-level exposure. This study was to explore the toxic effect and mechanisms of low-dose exposure of silica nanoparticles (SiNPs) on cardiac function in zebrafish embryos via the intravenous microinjection. The dosage of SiNPs was based on the no observed adverse effect level (NOAEL) of malformation assessment in zebrafish embryos. The mainly cardiac toxicity phenotypes induced by… CONTINUE READING
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World Health Statistics

  • World Health Organization.
  • Available at: http://www.who.int/gho/publications…
  • 2014

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