Low-dose endotoxemia and human neuropsychological functions

@article{Krabbe2005LowdoseEA,
  title={Low-dose endotoxemia and human neuropsychological functions},
  author={Karen Su{\'a}rez Krabbe and Abraham Reichenberg and Raz Yirmiya and Annelise Smed and Helle Bruunsgaard},
  journal={Brain, Behavior, and Immunity},
  year={2005},
  volume={19},
  pages={453-460}
}
Epidemiological data demonstrate an association between systemic low-grade inflammation defined as 2- to 3-fold increases in circulating inflammatory mediators and age-related decline in cognitive function. However, it is not known whether small elevations of circulating cytokine levels cause direct effects on human neuropsychological functions. We investigated changes in emotional, cognitive, and inflammatory parameters in an experimental in vivo model of low-grade inflammation. In a double… CONTINUE READING

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