Low-dose diclofenac, naproxen, and ibuprofen cohort study.

  title={Low-dose diclofenac, naproxen, and ibuprofen cohort study.},
  author={Susana Perez-Gutthann and Luis Alberto Garc{\'i}a-Rodr{\'i}guez and Alberto Duque-Oliart and Cristina Varas-Lorenzo},
  volume={19 7},
The risk of a newly diagnosed episode of upper gastrointestinal bleeding, acute liver and renal failure, agranulocytosis, aplastic anemia, severe skin disorders, and anaphylaxis was examined within 30 days after the first prescription for a low dose of diclofenac, naproxen, or ibuprofen in a cohort in the United Kingdom. We identified 22,146 persons using diclofenac (< or = 75 mg), 46,919 using naproxen (< or = 750 mg), and 54,830 using ibuprofen (< or = 1200 mg). Age, gender, and comorbidity… CONTINUE READING
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