Low-dose carbon monoxide treatment attenuates early pulmonary neutrophil recruitment after acid aspiration.

@article{Nemzek2008LowdoseCM,
  title={Low-dose carbon monoxide treatment attenuates early pulmonary neutrophil recruitment after acid aspiration.},
  author={Jean A. Nemzek and Christopher L. Fry and Omorodola I Abatan},
  journal={American journal of physiology. Lung cellular and molecular physiology},
  year={2008},
  volume={294 4},
  pages={L644-53}
}
Exogenous carbon monoxide (CO) has anti-inflammatory and cytoprotective properties that show promise in the treatment of numerous pulmonary diseases. However, the effectiveness of CO in acute pulmonary injury associated with direct lung insult has not been shown conclusively. The purpose of this study was to determine if exogenous CO would modulate the pulmonary inflammation and lung injury that develops after acid aspiration. Groups of mice were given intratracheal (IT) injections of either… CONTINUE READING