Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation

@inproceedings{Li2016LowdoseCN,
  title={Low-dose carbon-based nanoparticle-induced effects in A549 lung cells determined by biospectroscopy are associated with increases in genomic methylation},
  author={Junyi Li and Meiping Tian and Li Cui and John G. Dwyer and Nigel J Fullwood and Heqing Shen and Francis Luke Martin},
  booktitle={Scientific reports},
  year={2016}
}
Nanotechnology has introduced many manufactured carbon-based nanoparticles (CNPs) into our environment, generating a debate into their risks and benefits. Numerous nanotoxicology investigations have been carried, and nanoparticle-induced toxic effects have been reported. However, there remain gaps in our knowledge, primarily regarding mechanism. Herein, we assessed the global alterations induced by CNPs in A549 lung cells using biospectroscopy techniques, including attenuated total reflection… CONTINUE READING
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