Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.

@article{Wallenburg1986LowdoseAP,
  title={Low-dose aspirin prevents pregnancy-induced hypertension and pre-eclampsia in angiotensin-sensitive primigravidae.},
  author={Henk C. S. Wallenburg and Gustaaf Dekker and J W Makovitz and P Rotmans},
  journal={Lancet},
  year={1986},
  volume={1 8471},
  pages={1-3}
}
The possibility of preventing pregnancy-induced hypertension (PIH) and pre-eclampsia in primigravidae by suppressing production of thromboxane A2 with low-dose aspirin was investigated in a randomised, placebo-controlled, double-blind trial. 46 normotensive women at 28 weeks' gestation, judged to be at risk of PIH or pre-eclampsia because of an increased blood-pressure response to intravenously infused angiotensin II, were studied. 23 women received 60 mg aspirin daily, and the same number… CONTINUE READING

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