Low-dose aspirin in pregnancy.

  title={Low-dose aspirin in pregnancy.},
  author={Baha M. Sibai and Robert Mirro and C M Chesney and C T Leffler},
  journal={Obstetrics and gynecology},
  volume={74 4},
In a prospective study, we evaluated the effects of low-dose aspirin on maternal and neonatal plasma 6-keto-prostaglandin (PG) F1 alpha concentration, platelet aggregation, platelet thromboxane production, and neonatal transitional circulation. Forty women, at a mean (+/- SD) of 37 +/- 2 weeks' gestation, were randomized to receive (N = 10 each) placebo or 20, 60, or 80 mg of aspirin per day until delivery. Maternal serum 6-keto-PGF1 alpha levels were not affected by these doses of aspirin… CONTINUE READING


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