Low-dose and high-dose adrenocorticotropin testing: indications and shortcomings.

  title={Low-dose and high-dose adrenocorticotropin testing: indications and shortcomings.},
  author={Gabriel Dickstein and Leonard Saiegh},
  journal={Current opinion in endocrinology, diabetes, and obesity},
  volume={15 3},
PURPOSE OF REVIEW The 250 microg adrenocorticotropin test (high-dose test) is the most commonly used adrenal stimulation test, though the use of physiologic doses (1.0 microg or 0.5 microg/1.73 m) (low-dose test) has recently gained wider acceptance. These variants and the use of adrenocorticotropin test in the ICU, however, remain controversial. The validity of the low-dose test and the parameters for evaluation of high- and low-dose tests in different situations need reevaluation. RECENT… CONTINUE READING


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